tert-butyl 8-fluoro-1,2,3,5-tetrahydro-1,4-benzodiazepine-4-carboxylate - Names and Identifiers
Name | tert-butyl 8-fluoro-1,2,3,5-tetrahydro-1,4-benzodiazepine-4-carboxylate
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Synonyms | 4-N-Boc-8-fluoro-1,2,3,5-tetrahydro-benzo[e][1,4]diazepine tert-butyl 8-fluoro-1,2,3,5-tetrahydro-1,4-benzodiazepine-4-carboxylate tert-Butyl 8-fluoro-1,2,3,5-tetrahydro-1,4-benzodiazepine-4-carboxylate tert-butyl 8-fluoro-2,3-dihydro-1H-benzo[e][1,4]diazepine-4(5H)-carboxylate tert-Butyl 8-fluoro-1,2,3,5-tetrahydro-4H-benzo[e][1,4]diazepine-4-carboxylate 4H-1,4-Benzodiazepine-4-carboxylic acid, 8-fluoro-1,2,3,5-tetrahydro-, 1,1-dimethylethyl ester
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CAS | 886364-28-9
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InChI | InChI=1/C14H19FN2O2/c1-14(2,3)19-13(18)17-7-6-16-12-8-11(15)5-4-10(12)9-17/h4-5,8,16H,6-7,9H2,1-3H3 |
tert-butyl 8-fluoro-1,2,3,5-tetrahydro-1,4-benzodiazepine-4-carboxylate - Physico-chemical Properties
Molecular Formula | C14H19FN2O2
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Molar Mass | 266.31 |
Density | 1.145g/cm3 |
Boling Point | 367.4°C at 760 mmHg |
Flash Point | 176°C |
Vapor Presure | 1.37E-05mmHg at 25°C |
Storage Condition | 2-8°C |
Refractive Index | 1.515 |
tert-butyl 8-fluoro-1,2,3,5-tetrahydro-1,4-benzodiazepine-4-carboxylate - Introduction
tert-butyl 8-fluoro-1,2,3,5-tetrahydro-1, is a chemical compound whose molecular formula is C16H19FN2O2. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: It is a white or off-white crystalline solid.
-Melting point: Its melting point is about 68-70°C.
-Solubility: It can be dissolved in organic solvents (such as dimethyl sulfoxide, dichloromethane, etc.), but it is almost insoluble in water.
Use:
- tert-butyl 8-fluoro-1,2,3,5-tetrahydro-1, is an intermediate compound that is widely used in drug synthesis. It can be used to synthesize drugs with anxiolytic and sedative effects.
Preparation Method:
- tert-butyl 8-fluoro-1,2,3,5-tetrahydro-1, the preparation of fluorfn usually undergoes multiple steps of organic synthesis. One common method of preparation is the coupling of dihalobenzylamine with tert-butyl bromoacetate by reaction with the appropriate starting materials, such as in the presence of tetrahydropyrimidine.
Safety Information:
br>- tert-butyl 8-fluoro-1,2,3,5-tetrahydro-1, -It may cause irritation to the skin, eyes and respiratory tract, so wear appropriate personal protective equipment such as gloves, goggles and protective masks when handling.
-Avoid inhalation or contact with skin, eyes and clothing. After use, clean the contaminated area thoroughly.
Last Update:2024-04-09 20:49:11